Evaluating the antibacterial properties of chitosan fibres embedded with copper ions for wound dressing applications

Barnabus, John and Miraftab, Mohsen and Qinand, Yimin and Changjun, Zhu (2014) Evaluating the antibacterial properties of chitosan fibres embedded with copper ions for wound dressing applications. Journal of Industrial Textiles, 44 (2). pp. 232-244. ISSN 1528-0837

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Official URL: http://jit.sagepub.com/

Abstract

Chitosan is a natural polymer that is well known for its inherent antimicrobial ability and natural healing properties and hence it has been developed into fibres that are used for wound dressing applications. To increase its antimicrobial potency, these fibres are treated with copper sulphate. In a wound environment, copper ions have potent antimicrobial abilities due to their propensity to bind with proteins and ability to produce hydrogen peroxides. In this article, copper-treated chitosan fibres of different concentrations have been tested and analysed to determine the most effective antimicrobial dose for potential wound care dressings. Selected common skin microflora, i.e. Staphylococcus aureus, Staphylococcus epidermidis and Micrococcus luteus, have been used to test the chitosan–copper combinations. The analysis, based on the test methods of zone of inhibition, spectrophotometry and plating technique, has shown that copper concentration of 0.3 gm/ml was highly effective against the three bacteria and could potentially be most suitable formulation for wound dressing applications.

Item Type: Article
Additional Information: Full text of this article is not available in this repository.
Uncontrolled Keywords: Chitosan; copper sulphate; Micrococcus luteus; Staphylococcus aureus; Styphylococcus epidermidis
Subjects: T Technology > T Technology (General)
Divisions: University of Bolton Research Centres > Institute for Materials Research and Innovation
Depositing User: Sarah Taylor
Date Deposited: 24 Nov 2015 14:48
Last Modified: 24 Nov 2015 14:48
Identification Number: 10.1177/1528083713483782
URI: http://ubir.bolton.ac.uk/id/eprint/770

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