Leveraging antibacterial efficacy of silver loaded chitosan nanoparticles on layer-by-layer self-assembled coated cotton fabric

Gadkari, R.R., Wazed Ali, S., Joshi, Mangala, Rajendran, Subbiyan ORCID: 0000-0001-5321-0085, Das, A. and Alagirusamy, R. (2020) Leveraging antibacterial efficacy of silver loaded chitosan nanoparticles on layer-by-layer self-assembled coated cotton fabric. International Journal of Biological Macromolecules, 162 (1 Nov.). pp. 548-560. ISSN 0141-8130

Text LEVERAGING ANTIBACTERIAL EFFICACY -Final Manuscript - IJBM.pdf - Accepted Version Restricted to Repository staff only until 17 June 2021. Download (956kB)

Abstract

The present study relates to forma self-assembled coating on cotton fabric using layer-by-layer (L-B-L) technique to impart antimicrobial property. Poly(styrenesulfonate) (PSS) and synthesised silver loaded chitosan (CS-Ag) nanoparticles were used as anionic and cationic agents, respectively, for the L-B-L electrostatic assembly of polyelectrolytes. The alternate L B-L deposition of PSS and CS-Ag nanoparticles on fabric was done up to 15 bi-layers, which was confirmed by measuring the change in depth of colour of fabric after each single layer deposition. Scanning electron micrographs showed the successful deposition of CS-Ag nanoparticles as the topmost surface layer of coated fabric, which was further reaffirmed by X ray photoelectron spectroscopy analysis. Results of both qualitative and quantitative analysis showed enhancement in the antibacterial activity of fabric coated L-B-L with CS-Ag nanoparticles (using minimal loading of silver) with respect to that of fabric coated L-B-L with chitosan (CS) nanoparticles. This was further substantiated by sustained release of Ag+ from fabric coated L-B-L with CS-Ag nanoparticles, as observed by atomic absorption spectroscopy. Besides, no adverse effect on the physical and mechanical properties of the fabric, such as air-permeability, tensile strength and bending (flexural) rigidity, was observed after L-B-L coating of nanoparticles.

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