Ultrafast chemical-free cell lysis by high speed stream collision induced by surface acoustic waves.

Wang, Wenbo, Chen, Yishan, Farooq, Umar, Xuan, Weipeng, Jin, Hao, Dong, Shurong and Luo, J. ORCID: 0000-0003-0310-2443 (2017) Ultrafast chemical-free cell lysis by high speed stream collision induced by surface acoustic waves. Applied Physics Letters, 110 (143504). ISSN 0003-6951

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Official URL: http://aip.scitation.org/toc/apl/110/14?expanded=1...

Abstract

This paper reports on a surface acoustic wave(SAW) based cell lysis device on a LiNbO3 substrate by utilizing high speed collision of cells, which are accelerated by acoustic streaming. With varying working powers, cell lysis was achieved within 20 s and more than 95% lysis efficiency. The cell solution volume effect on SAW based lysis was also investigated and proved that it is not the main issue. With the CCK8 based viability test and verification of cell contents by electrophoresis, the efficient lysis results of our devices have been verified.

Item Type: Article
Additional Information: This article appeared in Applied Physics Letters 110, 143504 (2017); and may be found at http://aip.scitation.org/doi/pdf/10.1063/1.
Divisions: University of Bolton Research Centres > Institute for Renewable Energy and Environmental Technologies
Depositing User: Tracey Gill
Date Deposited: 04 Aug 2017 07:48
Last Modified: 18 Apr 2018 02:30
Identification Number: 10.1063/1.4979788
URI: http://ubir.bolton.ac.uk/id/eprint/1165

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